Dust / Waste Handling Systems particularly applicable to the handling of cotton / lint waste and associated trash created by machines in ginning plants. The system consists of a pneumatic ducting circuit connecting a filteration unit to all factory locations where waste and dust is generated. A fan creates an air flow in the ducting circuit to carry waste and dust therealong. The fan separates the air flow into major and minor portions and by centrifugal force transfers most of the waste and dust to the minor portion. The air in the major portion is directed back to the factory space via a filter to remove any dust contained in the major portion